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Saturday, 2 August 2014

Scientists create transparent mouse complete with see-through organs

The Independent 

Scientists have created see-through mice complete with transparent organs, in a new technique that could pave the way to a new generation of therapies for conditions ranging from autism to chronic pain. 

Mice are frequently used in biomedical research because much of their basic biology is similar to humans, meaning they can be altered in ways that simulate human diseases.

The transparent mice are not alive however, and are currently being used for scientists researching fine details of anatomy.

Vivian Gradinaru, a senior author of the study at the California Institute of Technology, said the research could pave the way for a better understanding of brain-body interactions, more accurate clinical diagnoses and disease monitoring.

Before being treated with chemicals, the mice were euthanised and their skin removed. The team then pumped a series of chemicals through blood vessels, as well as other passages in the brain and spinal cord.

Some of the chemicals form a mesh to hold tissue in place, while others wash out fats that make tissue block light. 

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