American scientists controversially recreate deadly Spanish Flu virus

The Independent

The extinct influenza virus that caused the worst flu pandemic in history has been recreated from fragments of avian flu found in wild ducks in a controversial experiment to show how easy it would be for the deadly flu strain to reemerge today.

Scientists said the study involved infecting laboratory ferrets with close copies of the 1918 virus – which was responsible for the Spanish Flu pandemic that killed an estimated 50 million people – to see how easy it can be transmitted in the best animal model of the human disease.

But other researchers have denounced the research as foolhardy and dangerous. Critics said that any benefits of the attempts to recreate 1918-like flu viruses from existing avian flu strains do not justify the catastrophic risks if such a genetically engineered virus were to escape either deliberately or accidentally from the laboratory and cause a deadly influenza pandemic.

Read more

Too late to contain killer flu science, say experts

Independent

Attempts to censor details of controversial influenza experiments that created a highly infectious form of bird-flu virus are unlikely to stop the information from leaking out, according to scientists familiar with the research. The US Government has asked the editors of two scientific journals to refrain from publishing key parts of research on the H5N1 strain of bird-flu in order to prevent the information falling into the hands of terrorists intent on recreating the same flu strain for use as a bioweapon. However, scientists yesterday condemned the move.

Some said that the decision comes too late because the information has already been shared widely among flu researchers, while others argued that the move could obstruct attempts to find new vaccines and drugs against an infectious form of human H5N1 if it appeared naturally. 

Professor Richard Ebright, a molecular biologist at Rutgers University in Piscataway, New Jersey, said that the research, which was funded by the US Government, should never have been done without first assessing the risks and benefits. “The work posed risks that outweighed benefits and that were clearly foreseeable before the work was performed,” Professor Ebright said. “The work should have been reviewed at the national or international level before being performed, and should have been restricted at a national or international level before being performed,” he said.

Read more

Mad Scientists Create H5N1 GM BioTerrorism Virus

Conspiracy Planet 

Locked up in the bowels of the medical faculty building here and accessible to only a handful of scientists lies a man-made flu virus that could change world history if it were ever set free. 

The virus is an H5N1 avian influenza strain that has been genetically altered and is now easily transmissible between ferrets, the animals that most closely mimic the human response to flu. 

Scientists believe it's likely that the pathogen, if it emerged in nature or were released, would trigger an influenza pandemic, quite possibly with many millions of deaths.

In a 17th floor office in the same building, virologist Ron Fouchier of Erasmus Medical Center calmly explains why his team created what he says is "probably one of the most dangerous viruses you can make" -- and why he wants to publish a paper describing how they did it. Fouchier is also bracing for a media storm. After he talked to ScienceInsider yesterday, he had an appointment with an institutional press officer to chart a communication strategy.

Read more