Science Daily
The findings come as the World Health Organisation has announced a new Ebola virus outbreak in the Democratic Republic of Kongo.
The team analysed the prospects for various Ebolavirus vaccines and found that, for the foreseable future at least, Ebolavirus outbreak control depends on surveillance and the isolation of cases.
The researchers' analysis revealed that very high proportions of potentially affected populations would need to be protected by vaccination to establish herd immunity, i.e. the level of immunity that prevents virus transmission within a population.
The study, entitled Herd immunity to Ebolaviruses is not a realistic target for current vaccination strategies identified that, in the critical phases of many Ebola virus outbreaks, the average infected individual infects four or more other people, which enables the virus to spread rapidly.
At this level, 80% of a population would need to be immunised to prevent outbreaks, even if a highly effective vaccine that protects 90% of individuals after vaccination was available.
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Prophylactic mass vaccination programmes are not a realistic option in the battle to prevent new Ebolavirus outbreaks, a University of Kent-led research team has shown.
The team analysed the prospects for various Ebolavirus vaccines and found that, for the foreseable future at least, Ebolavirus outbreak control depends on surveillance and the isolation of cases.
The researchers' analysis revealed that very high proportions of potentially affected populations would need to be protected by vaccination to establish herd immunity, i.e. the level of immunity that prevents virus transmission within a population.
The study, entitled Herd immunity to Ebolaviruses is not a realistic target for current vaccination strategies identified that, in the critical phases of many Ebola virus outbreaks, the average infected individual infects four or more other people, which enables the virus to spread rapidly.
At this level, 80% of a population would need to be immunised to prevent outbreaks, even if a highly effective vaccine that protects 90% of individuals after vaccination was available.
Read more
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